Problem: A patient with Parkinson's disease is prescribed Levodopa. The patient's spouse asks about long-term usage of this medication. Which of the following may the nurse share? Over time the body's response to Levodopa increases, so the dosage is normally lowered. To maintain the effectiveness of Levodopa, it is best to cycle on and of the medication. Because of its toxic side effects, levodopa can only be used for 1 to 2 years. After several years of use, the effectiveness of Levodopa may decrease. Looking for Assignment Help?