Problem: Client is receiving tacrolimus (Prograf) to prevent organ rejection. Which of the following is a nursing considerations associated with this medication? A client is receiving tacrolimus (Prograf) to prevent organ rejection. Which of the following is a nursing considerations associated with this medication? Give with cyclosporine (Sandimmune). Assess platelet count for thrombocytopenia. Give with grapefruit juice. Assess for hypoglyemi