Question: The nurse is asked to explain the physiologic changes that occur with heart failure. Which information should the nurse include in response? Question options: 1) The walls of the heart shrink, leading to lower cardiac output. 2) Blood backs up into the lungs due to right-ventricular hypertrophy. 3) Blood pressure increases, resulting in lowered afterload. 4) Cardiac remodeling occurs after prolonged ventricular hypertrophy.