Methotrexate-potent cancer chemotherapeutic agent
Methotrexate, a potent cancer chemotherapeutic agent, is a strong competitive inhibitor of the dihydrofolate reductase. Explain why this compound is an efficient inhibitor of the de novo synthesis of both purine and thymidine nucleotides.
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Though the enzyme Trypsin was capable to hydrolyze both TAME and BTEE substrates and I was wondering why? And why/ what makes chymotrypsin so much more precise??
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Please explain whether clinical practice guidelines exist for schizophrenia in older adults, and if so, use them to justify your recommendations.
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