Question 1) What are clinical trials ? Explain different phases of clinical trials.
Question 2) Explain dosage form. Describe in detail classification of dosage form. Add a note on sustained release and targeted drug delivery system.
Question 3) Attempt the following:
a) Explain pharmaceutics and explain its scope.
b) What is first pass effect?
c) Add a note on drug efficiency and dose response concept.
d) Mention applications of radiopharmaceuticals.
e) Give the importance of GMP.
f) Describe principle of Unani and Siddha system of medicine.
g) Explain antioxidants used in formulation.
Question 4) Write brief notes:
a) Packaging of tablet
b) Concept of preformulation
c) Bio-availability and bio-equivalence
d) Development of profession of pharmacy
e) Routes of administration
Question 5) What are aromatic waters? Describe the methods of preparation and preservation of aromatic waters.
Question 6) Explain the principle, construction, working, advantages and applications of plate and frame filter press.
Question 7) Answer the following questions
a) Describe why preservatives are not required in simple syrup I.P.
b) Discuss formulation of linctuses.
c) Explain factors affecting size reduction.
d) Write a detail note on propeller mixer.
e) Explain the importance of filter aids.
f) Describe different methods of granulation.
g) Write a note on tooth powder.
Question 8) Answer the following questions:
a) Explain the process of size gradation and size distribution.
b) Explain construction, working and application of Ball mill.
c) Discuss formulation and manufacturing process involved in liquid oral preparation.
d) Write note on:
i) Rotary filter
ii) Planetary mixer.
e) Discuss methods used for improvement of solubility.