Method for fractionation of subcellular organelles
In order to study the composition and the metabolic role of the various subcellular organelles in a cell, it becomes necessary that each of the organelle is isolated from - the cell. In fact, in biochemical work, the isolation of the individual organelles from the cell is the first step in metabolic studies. The difference in the densities of organelles help in isolating them from each other. Hence, by a process of differential centrifugation, the organelles of a cell may be separated from one another.