Case study
A 16 month old infant presents with severe disseminated mycobacterial infection, and was previously treated for a Cytomegalovirus infection. The child has fever, sweating and diarrhoea, and abdominal tenderness and lymphadenopathy on examination.
1. What component of the immune system may be defective?
2. Discuss likely diagnoses from the clinical picture.
3. What are the associated pathways involved?
4. Discuss how signalling would normally protect the patient, and how the defect impacts the immune response.
The accepted referencing style for this assignment is: Harvard or Vancouver
Word limit for this assignment is 1500 in total, and DOES NOT include text in the bibliography/reference list, figure legends and tables (if relevant).
However, students cannot use figure legends or text within tables to try and side step the word limit (i.e. figure legends and table must be of 200
words or less). Penalties for exceeding work limits are as follows (according to faculty guidance):
- Up to 10% over limit: mark reduced by 10%
- 11%-20% over limit: mark reduced by 25%
- 21%-50% over limit mark reduced by 50%
- over 51% over work will not be marked
How students receive their assignment mark and associated feedback will be programme specific.
Any queries regarding this assignment should be directed to your own programme in the first instance.