Problem: A 26-year-old man with a history of depression has been taking fluoxetine 40 mg/day for 12 weeks with no response. The patient has no other comorbid medical or psychiatric conditions and has only trialed fluoxetine for his depression. All laboratory values are within normal limits and his urine drug screen is negative for all drugs of abuse. The physician asks for a recommendation for the patient. Which of the following is the most reasonable recommendation to provide? Need Assignment Help?
Group of answer choices
- Switch to venlafaxine
- Decrease fluoxetine to 20 mg/day
- Increase fluoxetine to 60 mg/day
- Switch to nortriptyline