Twelve patients having high albumin content in their blood were treated with a medicine. Their blood content of albumin was measured before and after treat- ment. The measured values are shown in the table.
Blood Content of Albumina a Values given in grams per 100 ml.
|
Patient
|
Before Treatment
|
After Treatment
|
|
1
|
5.02
|
4.66
|
|
2
|
5.08
|
5.15
|
|
3
|
4.75
|
4.30
|
|
4
|
5.25
|
5.07
|
|
5
|
4.80
|
5.38
|
|
6
|
5.77
|
5.10
|
|
7
|
4.85
|
4.80
|
|
8
|
5.09
|
4.91
|
|
9
|
6.05
|
5.22
|
|
10
|
4.77
|
4.50
|
|
11
|
4.85
|
4.85
|
|
12
|
5.24
|
4.56
|
Is the effect of the medicine significant at the 5 percent level?
• Use the sign test.
• Use the signed rank test.