Insulin is released into the bloodstream by the β cells of the pancreas when blood glucose stages are high after feeding and stimulates glycogen synthesis to kept excess glucose as glycogen. This organize is also achieved by phosphorylation events. Insulin connecting to its receptor in the plasma membrane and activates it. This receptor has tyrosine kinase movement example for it will phosphorylate selected tyrosine residues on target proteins. Its starts lead to the activation of an insulin-responsive protein kinase in which then phosphorylates protein phosphatase I, thus activating it. This enzyme now makes sure that glycogen synthase is dephosphorylated and thus active and which phosphorylase kinase is also dephosphorylated (and therefore inactive). The net effect is to stimulate glycogen synthesis.