How would hypergammaglobulinemai affect the test for rf


Problem

I. What is the lupus anticoagulant, and how can it interfere in coagulation testing, specifically the PT and PTT leading to a misdiagnosis.

II. How would hypergammaglobulinemai affect the test for RF?

III. Explain why in systemic inflammatory disorders complement proteins, namely C3 may be low.

IV. What is the most common fluorescent tag used in direct fluorescent antibody techniques?

V. Draw and explain each of the following reactions in an Ochterlony Double Disc Diffusion reaction.

i. Pattern of Identity:
ii. Pattern of non-identity:
iii. Pattern of partial identity:

VI. Should someone have a positive RF, is that diagnostic of RA? Why or why not?

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