How same gene can cause different types of cancer

Question

Assignment:

Answer the following questions in 4 to 5 pages:

1. Do Web research or consult in the textbook to name a gene, other thanBRCA1, that increases risk of developing breast cancer when mutant. What is the process or mechanism that the mutation disrupts?
2. Discuss how alternate splicing can complicate the study of mutations in the BRCA1gene.
3. Distinguish between a hereditary germline cancer, such as those caused by BRCA1mutations, and cancers that result from two somatic mutations in the same gene in the same cell.
4. Explain how mutations in the same gene can cause different types of cancer.