How many extra hydrogen bonds need to be formed, Chemistry

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How many extra hydrogen bonds need to be formed

Problem

How many extra hydrogen bonds need to be formed in the transition state for an enzymatically catalyzed reaction to increase by 104 times at 37^oC? The answer must be calculated, all steps in the calculations must be reported and all units must be stated. For assumptions about the size of a hydrogen bond strength, a source reference must be given.

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