Problem
Watch the video below by Dr Jason Fung as he explains why the CICO - Calories In and Calories Out is not a valid concept in human metabolism. Also recalling the video by Dr. Zoe Harcombe, Compare and Contrast the CICO with the hormonal and 'Set Point' model as discussed by Dr Fung and Dr Harcombe. How does this explain the failure of people to both lose weight, and if lost, to keep the weight off?