How does alcohal affects humain brain tissue


Problem:

My Russian friend says that the USSR agents used/use the trick that they offered the victim first vodka and then last wine.
I have noted that this puts you faster to hangover: decreasing the alcohol proof. Some people lose their motor function immediately and some their memory only.

Question: Why does a decrease in alcohol proof cause you

a) faster intoxication and

b) faster hangover?

Probably the change in the concentration of alcohol inside cells of brain tissue affects some parts of your brain like the cerebellum. I would like to have an explanation in Biochemistry.

Question: Is there any truth in this argument?

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Biology: How does alcohal affects humain brain tissue
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