How do toxic compounds harm our tissues

Question

Problem:

During the alcohol metabolic pathway, harmful by-products are made like acetaldehyde, hydroxyethyl, superox­ide anions, and hydroxyl radicals.

Required:

Question: How do these toxic compounds harm our tissues?

Question: Many of these intermediates are the compounds that are responsible for hangovers, but are they also the molecular cause of liver damage?

Explain your reasoning.