Solved: Haplotype frequencies and the allele freqencies, Basic Statistics

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Haplotype frequencies and the allele freqencies

Discussion:

Statistical Genetics: Linkage Disequilibrium Question

Task:

1500 people were genotyped at two loci, G and H. Each locus had two alleles (G/g and H/h). The results were (frequency given for each two-locus genotype):

Two-locus genotype Frequency

GGHH 0.1020

GgHH 0.1341

ggHH 0.0441

GGHh 0.1209

GgHh 0.2592

ggHh 0.1182

GGhh 0.0358

Gghh 0.1065

gghh 0.0790

Q: What is the number of observed GH, Gh, gH, and gh haplotypes given that the GgHh genotype class contained 270 haplotypes? What are the haplotype frequencies and the allele freqencies?

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Basic Statistics: Haplotype frequencies and the allele freqencies

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Basic Statistics: Haplotype frequencies and the allele freqencies

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