Problem 1: Discuss the following statement: "All small molecule drugs are synthetic, and all peptide drugs are biopharmaceuticals". Describe 2 common advantages and 2 common disadvantages of protein drugs versus small molecule drugs. For each, include an explanation as to why this advantage or disadvantage is present.
Problem 2: As the head of a research laboratory, what general experimental approach might you use to discover a disease modifying gene for epilepsy. Describe the 3 categories of disease modifying gene that you might reveal, and whether or not they are all likely to be druggable, and why.