For which drugs is a physiologic result used, Biology

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For which drugs is a physiologic result used

Problem: Therapeutic drug monitoring is done for many drugs. The actual drug concentration in the blood can be measured or a physiologic result of the drug's action can be assessed. For which of the drugs listed below is a physiologic result used?

Potassium bromide
Phenobarbitol
Levothyroxine
Digoxin

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Biology: For which drugs is a physiologic result used

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