Problem 1: A bacterium from a bacterial infection in an individual avoided the lysis and opsonisation by the complement proteins. Explain the different scenarios that could have occurred and would have led to this infection?
Problem 2: Macrophages play a central role in chronic inflammatory disorders. Justify this statement by explaining the concept of inflammation and by giving examples of where this takes place.
Problem 3: William Tucker is a 31-year-old male who developed an infection followed by an increase in the secretion of cytokines and overactivation of T cell response. The diagnostic analysis suggested a bacterial toxin in the body. What is the most probable reason for the cytokine storm, and explain this phenomenon?