Question 1) Phage P1 has the double-stranded DNA with 91,5000 base pairs. Compute how many full double-helical turns does this DNA have. Is NADPH produced or utilizes in glycolysis, citric acid cycle, and electron transport chain?
Question 2) A main concept of gene theory of inheritance is that genes are located in chromosomes. Describe how each of the given below aids to establish this concept:
i) A genotypic ratio of 1:2:1 in offspring of heterozygotes.
ii) Phenomenon of crossing over.
iii) Other chromosomal aberrations.
iv) The phenomenon of sex determination, as in man.
Question 3) Henry is in hospital, having had mild heart attack. He is feeling very fine now and is about to be released. He turns to you and speaks, as he feels as fine as new, that he will be returning to his high-stress, physically demanding job as the professional football line-backer. What will you say to him and why?
Question 4) There are a range of reasonably ordinary human genetic diseases in which enzymes need for the breakdown of lactose, fructose or sucrose are faulty. Though, there are very little cases of people having genetic disease in which one of enzymes of glycolysis is harshly affected. Describe why do you assume such mutations are seen hardly ever?