Explain which of the subsequent statements accurately explain the insulin receptor? There is more than one correct answer. Select all the true state?
1. The structure comprised a transmembrane helix.
2. Insulin binds to the extracellular domain.
3. Insulin binding is needed for autophosphorylation (cross-phosphorylation).
4. The α subunit contains seven α helices that span the membrane.
5. Insulin binding promotes the dimerization of the receptor.
6. GTPase activity is needed for autophosphorylation (cross-phosphorylation).