Explain the Reduction in free radical generation - Vitamin E?
1) Reduction in free radical generation: Vitamin E acts synergistically with selenium thereby reducing susceptibility of LDL lo oxidation, free radical generation and membrane damage. This antioxidant role of vitamin E together with selenium protects against cardiovascular diseases especially atherosclerotic lesions.
2) Regulation of the enzyme activities: Vitamin E regulates the activity of enzymes, δ-amino levulinic acid (ALA) synthetase in bone marrow and ALA dehydl-ase in liver.