Question 1: Explain the role of RNA polymerase (I) in the process of transcription.
Question 2: List two types of hereditary cancer treatment, the gene(s) affected in each, and the common sites of tumor formation associated with each.
Question 3: Please explain, in your own words, what a biomarker is and how biomarker testing is associated with cancer treatment.
Question 4: List three of the cellular hallmarks of cancer.
Question 5: Explain what sustained proliferative signaling means, and describe two different ways in which this is induced in cancer cells.
Question 6: Read the article Cancer's Trick for Dodging the Immune System, and answer the following questions:
a. Is PD-L1 a "good" molecule or a "bad" molecule in terms of cancer formation and spread? Please explain why you chose your answer by explaining what PD-L1 does.
b. What species was this study performed in?
Question 7: Describe the role of the signaling molecule, Merlin.
Question 8: List two types of cancers in which the NF2 gene and, as a result, the Merlin protein, is mutated.