Explain Isoniazid
It is the drug of choice for treatment of latent TB infection. It should be given for 9 months in a single daily dose of 300 mg for adults and 10 mg/kg (max 300 mg/day) for children, or twice weekly as 10-15 mg/kg (max 900 mg/dose) in adults and 20-30 mg/kg (max 900 mg/dose) in children. It is safe for treatment of latent TB in pregnancy.