Explain Adverse Effects of Oseltamivir
Nausea and vomiting can occur. Taking the drug with food decreases the incidence of nausea. In juvenile rats, very high doses of oseltamivir (~250 times the recommended pediatric dose) have been associated with deaths and unexpectedly high concentrations in brain, possibly related to an immature blood-brain barrier. Oseltamivir has been used in infants, but is FDA-approved only for patients 1 year and older.