Problem: Write this in simple words, You have correctly identified the focus on hydroxychloroquine and azithromycin as key variables in examining their impacts on COVID-19 patients. These variables are central to understanding the effectiveness of such treatments during the pandemic. The classification of the study design as Level 3 reflects its observational nature and the inherent limitations. Although the evidence can be insightful, the potential for biases and confounding factors makes such studies less robust compared to randomized controlled trials (Evans, 2003). As you noted, while not as strong as randomized trials, observational studies can still offer meaningful contributions when other designs are not feasible due to ethical or practical reasons. Need Assignment Help?