Most textbooks state that Lck is activated upon TCR stimulation, however evidence to support this conclusion is controversial.
Some data suggest that Lck is constitutively active, however additional studies suggest that Lck is indeed activated upon TCR stimulation.
Describe some of the experiments in the literature that examine this issue and discuss their strengths and weaknesses. State if you support the view that Lck becomes activated upon TCR stimulation and justify your conclusion.