Question: Which information should the nurse include in the education for a client with peptic ulcer disease prescribed omeprazole (Prilosec)? Select all that apply. Which information should the nurse include in the education for a client with peptic ulcer disease prescribed omeprazole (Prilosec)? Select all that apply. Omeprazole (Prilosec) should not be crushed or chewed. Omeprazole (Prilosec) is recommended for long-term treatment of peptic ulcer disease. Omeprazole (Prilosec) is best taken with yogurt. Omeprazole (Prilosec) should be administered before meals. Omeprazole (Prilosec) should be administered after meals.