Discuss the pathophysiology of acute renal failure


Discussion Post: Advanced Patho

A 28-year-old male presents to the primary care office for evaluation of left calf pain, swelling, and redness. He reports that this started one day ago and worsened today. He ran a 27-mile marathon 2 days ago and traveled for 3 hours in a car today. He reports slight pain on walking and a swollen red calf. He took Ibuprofen 600 mg twice today without relief. Patient reports being an experienced runner, running 3-5 miles daily.

Two possible diagnoses were considered: deep vein thrombosis (DVT) and rhabdomyolysis.

Stat ultrasound of left leg to rule out DVT was ordered and read as normal

CBC WNL

Creatine Kinase (CK) 23,000 U/L (normal 24-170 U/L)

BUN and Creatinine WNL

A diagnosis of rhabdomyolysis was made.

• Discuss the pathophysiology of acute renal failure in rhabdomyolysis.

The response must include a reference list. Using Times New Roman 12 pnt font, double-space, one-inch margins, and APA style of writing and citations.

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