Homework: Literature summary on Homology Modeling
The purpose of this homework is to summarize and evaluate existing "literature" (or published material) in order to establish current knowledge on the subject of homology modeling of proteins. You can use the paper that I posted or use some other from the literature but do not forget to cite them.
What format should you use for the review?
A literature review of formal academic writing includes:
1. Introduction
• It defines or identifies the general topic, provides an appropriate context for describing the available methods found in the literature.
2. Body
• It summarizes individual studies or articles with as much or as little detail as each merits according to its comparative importance in the literature, remembering that space (length) denotes significance.
• You should not keep the title Body in your report but instead create different titles relative to the content.
3. Conclusion
• It summarizes major contributions of significant studies and articles to the body of knowledge under review, maintaining the focus established in the introduction.
To guide you, you will find 2 articles about homology modeling, and a very recent research (from 2016) on the modeling of Zika virus proteins.
Your summary should answer the following questions in the body:
A. Define Comparative/Homology Modeling.
B. Enumerate the steps in Comparative/Homology Modeling?
C. What tools/software are needed for each steps.
D. Draw or provide a flow chart of the steps involved in homology protein structure modeling. (you can use an image found online (cite the source) or draw it yourself.)
E. Which are the most commonly used homology-modeling tools/software/websites?
F. What does template structure mean?
G. Can we trust the models obtained blindly?
H. What are the possible applications of Comparative/Homology Modeling?
I. Discuss one example of a homology modeling study.
Format your homework according to the give formatting requirements:
1. The answer must be double spaced, typed, using Times New Roman font (size 12), with one-inch margins on all sides.
2. The response also includes a cover page containing the title of the homework, the course title, the student's name, and the date. The cover page is not included in the required page length.
3. Also include a reference page. The references and Citations should follow APA format. The reference page is not included in the required page length.