Problem:
Can you dumb this down for me: Morphine reduces cortisol and noradrenaline, which could help protect neurons. However, its effects on human newborns during hypothermia are uncertain. Neonatal seizures are common in HIE and are suspected to be an independent cause of brain injury, so using antiepileptic drugs as adjuncts to TH is common. Monitoring antiepileptic drug levels is crucial, especially if redosing is necessary. It is important to note that hypothermia can prolong the clearance of such drugs in newborns with HIE, so careful attention is required when using these adjunctive treatments.