Question: You are seeing a patient who has been hospitalized for 21 days due to an episode of sepsis that may probably have been caused by IV drug use with insufficient use of sterile precautions. Culture identified infection with various micro-organisms. Testing for sensitivity and specificity isolated a fluoroquinolone that can be effective against all of them. Show the most pressing concern about this situation. Patients with impaired renal status due to sepsis are now being asked to withstand renal-depressing fluoroquinolones. Your patient's state of health is compromised overall. His immune system has been deranged by IV drug abuse. He cannot mount an effective immune response. He is probably allergic to fluoroquinolones because of his extensive exposure to narcotics. Sensitivity in the lab does not guarantee the ability to clear the bloodstream of infection. There are places in the body that harbor infectious agents and allow antibiotics to fail to kill them.