Problem 1: Discuss all the factors that impact the absorption of drugs taken via the oral route.
Problem 2: What is post-mortem re-distribution and why does it occur?
Problem 3: List (3) ways that drug interactions may impact adme, including the mechanism of the interaction.
Problem 4: Describe the metabolism of ethanol and how it relates to the development of tolerance and liver toxicity.
Problem 5: Discuss why lipid soluable drugs and chemicals are not likely to be detected in urine as the parent compound.
Problem 6: Describe a common mechanism by which cns depressant drugs have their activity on neuronal physiology and the consequences of overdose.
Problem 7: Prepare a list of the major neurotransmitters and describe the receptors, signal transduction mechanisms and responses.