Problem: The nurse should include which in-home management instruction for a child who's receiving desmopressin acetate for symptomatic control of diabetes insipidus? Give desmopressin acetate only when urine output begins to decrease. Increase the desmopressin acetate dose if polyuria occurs just before the next scheduled dose. Call the health care provider for an alternate route of desmopressin acetate when the child has an upper respiratory infection (URI) or allergic rhinitis. Clean skin with alcohol before applying the desmopressin acetate dermal patch.