Problem
Chen S, Underwood BR, Jones PB, Lewis JR, Cardinal RN. 2022. Association between lithium use and the incidence of dementia and its subtypes: a retrospective cohort study. PLOS Medicine. 19(3): e1003941.
Make sure it is that article with that title.
• Design an RCT on the prevention of progression to dementia in those with mild cognitive impairment (MCI) or early disease. Describe your study here.
• What would you control for in your study? How would you ensure that you're testing for the effect of lithium on dementia?