Assignment
Part A: Atherosclerotic plaque formation
• Describe the step for the formation of an atherosclerotic in the upper branch of the left coronary artery
o Include in your answer the pathological changes at the level of the artery
o Include in your answer the risk factors that would lead to this plaque formation
Rupture of a plaque in the left coronary artery
• Differentiate between a stable and unstable plaque.
o A stable adequate is blood flow and the symptoms quickly subside without any damage to the heart and dot not tend to form cloth.
o A Unstable plaque is restriction of blood flow in the coronary artery,
• Describe what happens when an unstable plaque rupture
• An unstable plaque going to be hemorrhage into the plaque or thrombotic occlusion of the vessel lumen.
• Describe what happens to the contents of a ruptured plaque of upper branch of the left coronary artery. Where could the contents go?
o What happens as it progresses through the coronary circulation?
o What areas of the heart will it affect?
Clouding the arteries to the heart.
Part B: Hypertension mechanisms and pathophysiology
• Describe the risk factors that contribute to hypertension
o Describe how the risk factors contribute to the development of hypertension salt intake, obesity and insulin resistance, the renin-angiotensin system, and the sympathetic nervous system.
• How do the various components of the autonomic nervous system influence blood pressure?
o Include in your answer the involvement of the parasympathetic and sympathetic nervous system?
o How does the renin-angiotensin-aldosterone (RAA) system influence blood pressure?
Renin is secreted from the juxtaglomerular apparatus of the kidney in response to glomerular under perfusion or a reduced salt intake. It is also released in response to stimulation from the sympathetic nervous system
• How is the diagnosis of hypertension made?
• What are the manifestations related to hypertension?
o Include in your answer target-organ damage
• How do medications act to control blood pressure?
o Include in your answer, what are some non-pharmacological interventions to manage blood pressure, how do they help?
Format your assignment according to the give formatting requirements:
• The answer must be using Times New Roman font (size 12), double spaced, typed, with one-inch margins on all sides.
• The response also includes a cover page containing the student's name, the title of the assignment, the course title, and the date. The cover page is not included in the required page length.
• Also include a reference page. The references and Citations should follow APA format. The reference page is not included in the required page length.