Describe the pathogenic effects on cells, tissues, and organ systems.
1. Where in the body (what tissues/organs/cells) does the pathogen affect?
2. What damage does the pathogen inflict? How is this damage inflicted (is there direct
mechanical damage? is a toxin produced? does the immune response cause damage?)?
3. What is the time sequence of the disease (length of incubation, prodrome, illness, decline, and convalescence)?
4. What are the major signs and symptoms?