Problem:
Membranes disperse almost instantaneously if exposed to a nonpolar environment or to detergents, which are amphipathic molecules that can form a hydrophilic coat around the hydrophobic portions of membrane lipids and proteins in water solutions.
Required:
Question: If detergents can 'form coats around hydrophobic portions' of membrane-suspended molecules, they must, somehow get in the hydrophobic membrane interior... right?
Question: How do they get in the membrane interior?
Question: Do they form clusters like endocytic vesicles?
Question: What happens after they form hydrophilic coats around hydrophobic molecule regions?
Any help would be greatly appreciated!