Problem: A 48-year-old female presents to her primary care physician with the concern of worsening fatigue over the past 3 months and chest pain on exertion. Past medical history is unremarkable with the exception of significant weight gain over the last two years Please describe a potential underlying mechanism for the elevated plasma cholesterol levels found in this individual. Triglycerides are within normal values in this individual. Describe how triglyceride levels would be normal but cholesterol levels could be elevated in this individual.