Problem: Describe how IRB protects human research participants. Describe the violations of the principles of the ethical practice of public health in the Tuskegee Syphilis Study and Havasupai "Diabetes Study." Be sure to address the following questions in alignment with the Tuskegee Syphilis Study and the Havasupai "Diabetes Study". What is the role of an Institutional Review Board (IRB)? What are the guidelines for informed consent?