Define effect of dietary fibre expect physiological effects?
In addition to all the physiological effects mentioned above, dietary fibre may exert other effects. Acetate and propionate enter the portal circulation, thus extending the effects of dietary fibre beyond the intestinal tract. Initial in-vitro experiments have indicated that cholesterol synthesis by isolated hepatocytes is inhibited by propionic acid. However, a wide variety of data from human and animal studies do not consistently support this finding. Thus, whether inhibition of cholesterol synthesis by propionate occur in-vivo at physiological concentration is not clear.