Define Drug effects on Metabolism of dietary components?
Drugs can also compete with, or inhibit, the metabolic conversion of some micronutrients to their active metabolites, particularly folate. Methotrexate (used in the treatment of some cancers) directly antagonizes folic acid metabolism by inhibiting the activity of enzyme dehyrofolate reductase. Similarly, anticonvulsants impair vitamin D metabolism with consequent disturbances in calcium metabolism which adversely effects on bone.
Dietnry Components: Drugs may also affect the metabolism of dietary components such as MAOI.