Problem: The nurse notes that a client with a mental health condition is prescribed a medication with a high therapeutic index. In which way would the nurse expect the dose of the medication to be affected? There is a small range between the drug taking effect and toxicity occurring. There is another drug that can be used at a lower dose to cause the same effect. There is a large range between the drug taking effect and the dose that causes toxicity. There are many receptors that the drug will occupy to create a desired effect.