Chymotrypsin was able to hydrolyse the substrate N-benzoyl-L-tyrosine ethyl ester (BTEE) but not able to hydrolyse the substrate p-toluene sulphonyyl-L-arginine methyl ester (TAME).
However the enzyme trypsin was able to hydrolyse both TAME and BTEE substrates, and I was wondering why? And what makes chymotrypsin so much more specific?