Bile salts or bile acids are polar derivatives of constitute and cholesterol the major pathway for the excretion of cholesterol in mammals. In the liver, the cholesterol is circulated into the activated intermediate cholyl CoA that then reacts either with the amino set of glycine to produce glycocholate with the amino group of taurine (H2N-CH2 -CH2 -SO3 -, a derivative of cysteine) to make taurocholate