Adverse Effects of Adefovir dipivoxil
Doses of adefovir used for HBV are generally well tolerated but may be associated with asthenia, headache, diarrhea and abdominal pain. Higher than recommended doses (30-60 mg/d) and pre-existing renal impairment are risk factors for azotemia and renal tubular dysfunction. Hepatitis flares may occur after adefovir is stopped.