Activators
Activity of many enzymes is influenced by certain ions called as activators. Large number of enzymes such as hexokinase that require ATF are also in need of divalent =cations like M+ or n". Many enzymes such as ATPase require monovalent cations like Na+, K' or N&' for maximum catalytic activity. Amylase requires C1-. - Generally, these ions interact with the substrates so that the substrates can bind with the catalytic sites of the enzyme properly. Thus, in absence of the activators, the enzymes become inactive or sluggish.