How do I out the following questions in PICOT format?
1. Is chlorhexidine effective in decreasing topical infections?
2. How effective is chlorhexidine in decreasing resistant infections?
3. What are the systemic effects of chlorhexidine with daily use?
4. Will chlorhexidine contribute to pathogen resistance to antibiotics?
5. Should chlorhexidine be rinsed from the skin following application?