Strain improvement:
It is highly desirable that the industrial fermentation procedure must be made more and more economical. It largely depends upon the effectiveness of the production strain included in the fermentation procedure. Hence, a person interested in beginning a fermentation industry or in competing with other industries should procure a proficient strain. Therefore it is clear that, the utilization of a high yielding strain in any fermentation procedure is the most critical factor. Generally, newly isolated strains acquired by screening methods are not as efficient as could be employed in industrial fermentation processes. Thus, these strains need improvement, so far as the outcome of a particularly desired compound is concerned. This is accomplished by generating the mutant fermentation strains with the aid of physical and chemical techniques. The strain enhancement can be completed by auxotrophic mutants and mutant’s resistant to analogues. Microbial cultures that have multivalent mechanisms, concerted suppression or feedback inhibition might be employed for strain enhancement.
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